Medical Biochemistry Molecular and Cell Biology II

The subject addresses the metabolic processes in the human organism at molecular level with special emphasis on their medical aspects. The main topic is the metabolism of carbohydrates, lipids, amino acids and nucleotides and its regulation under normal and pathological conditions.

Lectures cover the following topics:
– Metabolism of compounds providing energy for the cell function.
– Storage and mobilization of carbohydrates and lipids.
– Gluconeogenesis and biosynthesis of sugar derivatives.
– Biosynthesis of fatty acids, triacylglycerols, phospholipids, cholesterol, bile acids.
– Turn-over of proteins in the human organism.
– Degradation of amino acids and metabolic fate of their carbon atoms.
– Formation and elimination of ammonia.
– Biosynthesis of non-essential amino acids.
– Biosynthesis and degradation of nucleotides and heme.

Students perform laboratory experiments that help them to acquire skills in basic biochemistry techniques. Selected pathological aspects of metabolism are discussed in seminars using problem-based learning in order to help students to apply their basic theoretical knowledge in solving medical problem.

Info-booklet 2012-2013 fall semester.