List of publications 2002

  • Bak J, Billington RA and Genazzani AA: Effect of luminal and extravesicular Ca2+ on NAADP binding and release properties Biochem. Biophys. Res. Com. 2002; 295:806-811
  • Bauer PI, Mendeleyev J, Kirsten E, Comstock JA, Hakam A, Büki KG and Kun E: Anti-cancer action of 4-iodo-3-nitro-benzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose)polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose)polymerase protease Biochemical Pharmacology, 2002; 63, 455 - 462
  • Darvas F , Keserű G, Papp Á, Dormán Á, Ürge L, Krajcsi P: In Silico and Ex Silico ADME Approaches for Drug Discovery Current Topics in Medicinal Chemistry, 2002; 2, 1287-304
  • Darvas F, Szabó I, Karancsi T, Slégel P, Dormán G, Ürge L, and Krajcsi P: Tutorial: Dual Uses of in silico and in vitro metabolism data in lead discovery - ComGenex' MAID: A metabolism-alerting system for early-phase discovery research Genetic Engineering News, 2002; 22 (10): 32
  • Dénes L, Hargitai I, Pénzes Z, Jednákovits A, Krajcsi P and Csermely P: Pharmacological activated migration of aortic endothelial cells is mediated through the p38 SAPK British Journal of Pharmacology, 2002; 136, 597-603
  • Dömötör E, Bartha K, Machovich R and Ádám-Vizi V:: Protease-activated receptor-2 (PAR-2) in brain microvascular endothelium and its regulation by plasmin and elastase.J. Neurochem. 2002; 80: 746-754 .
  • Habib NA, Mitry R, Seth P, Kuppuswamy M, Doronin K, Tóth K, Krajcsi P, Tollefson AE, Wold WSM: Adenovirus replication-competent vectors (KD1, KD3) complement the cytotoxicity and transgene expression from replication-defective vectors (Ad-GFP, Ad-Luc) Cancer Gene Therapy 2002: 9 651-654
  • Karnicki K, Komorowicz E, Fass DN, Owen WG and McBane RD: Influence of anatomical location on arterial thrombosis Arterioscler Thromb Vasc Biol 2002; 22: 342-347
  • Kolev K, Gombás J, Váradi B, Skopál J, Mede K, Pitlik E, Nagy Z and Machovich R.: Immunoglobulin G from patients with antiphospholipid syndrome impairs the fibrin dissolution with plasmin. Thromb Haemost 2002; 87: 502-508 user ID:7395
  • Komorowicz E, McBane RD, Charlesworth J and Fass DN: Reduced high shear platelet adhesion to the vascular media: Defective von Willebrand factor binding to the interstitial collagen Thromb Haemost, 2002; 87: 763-70
  • Komorowicz E, McBane RD and Fass DN: Physical and enzymatic perturbation of the architecture of the tunica media destroys its inherent thromboresistance. Thromb Haemost 2002; 88: 827-33.
  • Kun E and Bauer PI: Cell biological functions of PARP I: an overview. Italian Journal of Biochemistry, 2001; 50, 15-18
  • Lichtenstein DL, Krajcsi P, Esteban DJ, Tollefson AE, Wold WSM: Adenovirus RID beta subunit contains a tyrosine residue that is critical for RID-mediated receptor internalization and inhibition of Fas- and TRAIL-induced apoptosis Journal of Virology 2002: 76 (22): 11329-11342
  • Machovich R: A fibrinolysis modulátorai. Orvosi Hetilap 2002; 143: 541-545.
  • Tenekedjiev K and Kolev K: Introduction to Interpretation of Stochastic Parameters. Computer-Intensive Procedures for Evaluation of Data in Enzyme Kinetics Biochemistry and Molecular Biology Education 2002; 30: 414-418
  • Töröcsik B, Angelastro JM and Greene LA: The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth. J Neurosci. 2002; 22(20):8971-80
  • Tretter L. and Ádám-Vizi V.: Glutamate release by an Na+ load and oxidative stress in nerve terminals: relevance to ischemia/reperfusion. J. Neurochem. 2002, 83, 855-862
  • Visy J, Fotos I, Mády G, Ürge L, Krajcsi P and Simonyi M: Enantioselective plasma protein binding of bimoclomol Chirality, 2002, 14, 638-642


  • Bauer PI, Kénesi E and Illés A: Caspases: the regulators and excecutioners of apoptosis In: Molecular pathomechanisms and new trends in drug research (eds: Kéri, G. and Tóth, I.), Harwood Academic Publishers (The Netherlands), 2002; pp 100 - 109
  • Bauer PI and Kénesi E: A kaszpázok az apoptózis szabályozói és végrehajtói In: Apoptózis (eds: Kopper, L. and Fésűs, L.) 2002; 125 - 142
  • Krajcsi P: Signal transduction in virus infected cells - Implication for therapy In: Primer on molecular pathomechanisms ( Eds. G. Kéri, I. Tóth), 2002; pp 261-270, Taylor & Francis, London & New York
  • Krajcsi P: Apoptózist reguláló génfunkciók, In: Apoptózis, a sejthalál mechanizmusa (Szerk. Fésűs L. és Kopper L.) 2002; pp 285-296, Medicina, Budapest
  • Krajcsi P and Darvas F: HT in vitro toxicology In High-throughput ADMETox estimation: in vitro and in silico approaches, (Eds. G. Dormán and F. Darvas) 2002; pp75 BioTechniques Press, Eaton Publisher, Westborough, MA


  • Machovich R: Interaction of proteases with endothelial cells. ISP2002 4th International Congress of Pathophysiology, Budapest, Hungary (2002). (meghívott előadás)
  • Machovich R: A véralvadás, ami érdekes a klinikusnak. MOTESZ 2002. évi harmadik interdiszciplináris fóruma, Budapest, 2002: március 1. (meghívott előadás)
  • Machovich R.: Tumor metasztázis-hemosztázis. A Magyar Thrombosis és Haemostasis Társaság Debreceni Szimpoziuma és a Magyar Laboratóriumi Diagnosztikai Társaság Haemostasis Munkacsoport Fóruma, Debrecen, 2002: október 10-12. (meghívott előadás)


  • Darvas F, Dorman G, Krajcsi P, Urge L: A photoactivatable library approach for target identification and validation. Abstracts of the papers of the American Chemical Society 2002: 223: 245
  • Machovich R: Interaction of proteases with endothelial cells. ISP2002 4th International Congress of Pathophysiology, Acta Physiol Hung. 2002: 89: 40, Budapest, Hungary